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N-acetylcysteine helps make glutathione, a key anti-inflammatory molecule

It exerts a wide range of protective effects on the GI tract, including: Aiding the healing of lesions Guarding against the harmful effects of drugs Maintaining the integrity of the gastrointestinal mucosa [8–10] Neuroprotection In cases where the brain or spine has been injured, the anti-inflammatory, angiogenic, and growth factor modulatory activities of BPC-157 are beneficial in preventing secondary damage and accelerating recovery

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Lubiprostone is included within the list of drugs for the treatment of stress-induced gut-barrier dysfunction found in IBS, whose clinical manifestations includes constipation, bloating, and abdominal pain [119]